基因组与环境的关联分析揭示了的气候驱动的适应
Xiurong Zhao1, Jinxin Zhang2, Junhui Wen3
1College of Grassland Science and Technology, China Agricultural University, Beijing, 100193, China.
Genetics, selection, evolution : GSE
|July 22, 2025
概括
家显示出对气候的遗传适应. 研究人员确定了184个与气候相关的基因和5个特定的SNP,揭示了这些重要的食物动物中强大的选择性压力.
科学领域:
- 基因组学就是基因组学.
- 动物科学动物科学
- 进化生物学 进化生物学
背景情况:
- 在全球范围内具有重要意义,具有适应能力,因此它们是气候适应研究的理想模型.
- 了解适应的遗传机制对于家禽科学和保护至关重要.
- 温度和降水等环境因素对全球的种群有很大的影响.
研究的目的:
- 为了研究家气候适应的遗传基础.
- 识别与温度和降水相关的基因和遗传变异.
- 分析各种全球气候的土著品种的基因组-环境关联.
主要方法:
- 来自不同环境的199只本土的全基因组测序.
- 进行三项基因组环境关联分析.
- 使用单核酸多态性 (SNP) 和扩展的单核型同胞性 (EHH) 分析.
主要成果:
- 确定了184个潜在参与气候适应的候选基因.
- TSHR基因和与免疫相关的基因显示在适应中的潜在作用.
- 在ZNF536,ENSGALG00000049158,PAPPA和EHMT1中发现了五个SNP,它们具有明显的地理模式.
- EHH的分析表明,这些确定的位置受到强大的选择性压力.
结论:
- 这项研究为家气候适应的遗传基础提供了新的见解.
- 这些发现有助于理解对环境变化的反应进化过程.
- 已识别的基因和SNP为未来的家禽遗传学和适应性研究提供了目标.
相关概念视频
Background and Environment Affect Phenotype
6.7K
Although the genetic makeup of an organism plays a major role in determining the phenotype, there are also several environmental factors, such as temperature, oxygen availability, presence of mutagens, that can alter an organism’s phenotype.
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
6.7K
Natural Selection and Adaptation
396
Natural selection, a fundamental concept in evolutionary biology, is the mechanism by which evolution is driven, favoring organisms that are best adapted to their environments. This process enhances their chances of survival and reproduction. Adaptation, a key outcome of this process, involves genetic modifications that optimize an organism's functionality under specific environmental challenges, such as extreme cold or thinner air at high altitudes.
Beyond physical adaptations,...
Beyond physical adaptations,...
396
Gene-Environment Interactions
517
Gene expression is a dynamic process that is significantly influenced by environmental factors. This interaction underlies the complex nature of biological development and the phenotypic differences observed among individuals, even among those with identical genetic makeups. Factors such as radiation, temperature, behavior, nutrition, and stress play pivotal roles in determining how genes are expressed. The concept of the reaction range is central to understanding this interaction. It posits...
517
Transcription
148.4K
Overview
Transcription is the process of synthesizing RNA from a DNA sequence by RNA polymerase. It is the first step in producing a protein from a gene sequence. Additionally, many other proteins and regulatory sequences are involved in the proper synthesis of messenger RNA (mRNA). Regulation of transcription is responsible for the differentiation of all the different types of cells and often for the proper cellular response to environmental signals.
Transcription Can Produce Different Kinds...
Transcription is the process of synthesizing RNA from a DNA sequence by RNA polymerase. It is the first step in producing a protein from a gene sequence. Additionally, many other proteins and regulatory sequences are involved in the proper synthesis of messenger RNA (mRNA). Regulation of transcription is responsible for the differentiation of all the different types of cells and often for the proper cellular response to environmental signals.
Transcription Can Produce Different Kinds...
148.4K
Limits to Natural Selection
32.3K
Organisms that are well-adapted to their environment are more likely to survive and reproduce. However, natural selection does not lead to perfectly adapted organisms. Several factors constrain natural selection.
32.3K
What is Natural Selection?
119.0K
Natural selection is an evolutionary process in which individuals with survival-promoting traits reproduce at higher rates. These favorable traits become more common within a population or species. Naturally selected traits initially arise via random genetic mutations. In order for selection to occur, there must be variation within a population, the trait controlling the variation must be heritable, and there must be an evolutionary advantage for variation in the trait.
119.0K


