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在结直肠癌中检测瘤性融合,使用伴侣不可知的下一代测序方法

Andrew J Pellatt1, Reagan M Barnett2, Sante Gnerre2

  • 1Intermountain Health, Salt Lake City, USA. apellatt11@gmail.com.

BMC cancer
|July 22, 2025
PubMed
概括

伴侣不可知性ctDNA测试在1.3%的晚期结直肠癌 (CRC) 患者中发现了基因融合. 检测这些融合,特别是亚克隆的融合,可以指导向治疗,并揭示对EGFR抑制剂的耐药性机制.

关键词:
结肠直肠癌是一种癌症.欧洲农业基金会 (EGFR) 是一个基金.核聚变技术是可以实现的.ctDNActDNA是什么意思

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