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Updated: Sep 14, 2025

Accelerated Type 1 Diabetes Induction in Mice by Adoptive Transfer of Diabetogenic CD4+ T Cells
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尼沃卢马布剂量升级后1型糖尿病的发展:一个病例报告

Sayaka Mabuchi1,2, Naoko Adachi2, Atsushi Nagasawa2

  • 1Department of Human Resources Development for General Practitioner, Shimane Prefectural Central Hospital, Izumo, Japan.

Medicine
|July 23, 2025
PubMed
概括

高剂量的尼沃卢马布可能会增加免疫检查点抑制剂诱导的1型糖尿病 (ICI-T1DM) 的风险,特别是在体重较低的患者中. 剂量优化可以减轻这种风险,同时保持治疗疗效.

关键词:
免疫检查点抑制剂诱导的1型糖尿病免疫检查点抑制剂 免疫检查点抑制剂与免疫相关的不良事件.这就是尼沃卢马布 (nivolumab).编程细胞死亡-1 抗体

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