在 PROGRESS-BIFURCATION 注册表中验证V-RESOLVE 对侧枝阻塞的评分
Dimitrios Strepkos1, Michaella Alexandrou1, Deniz Mutlu1
1Minneapolis Heart Institute and Minneapolis Heart Institute Foundation, Abbott Northwestern Hospital, Minneapolis, Minnesota, USA.
概括
在冠状动脉分叉干预期间,V-RESOLVE得分显示侧枝封闭 (SBO) 的预测值适度. 较高的得分与增加的SBO风险和程序并发症相关,尽管总体上主要的心血管不良事件相似.
科学领域:
- 心血管医学 心血管医学
- 干预心脏病学 干预心脏病学
- 医疗器械技术 医疗器械技术
背景情况:
- 冠状动脉分支干预是复杂的程序,存在侧枝封闭 (SBO) 的风险.
- 在冠状动脉分支干预中侧枝闭塞风险预测的视觉估计 (V-RESOLVE) 评分是为了预测SBO而开发的.
研究的目的:
- 在一个独立的注册表中验证V-RESOLVE评分对SBO的预测性能.
- 评估V-RESOLVE得分与双叉穿皮冠状动脉干预 (PCI) 的程序结果之间的关联.
主要方法:
- 来自PROGRESS-BIFURCATION注册表 (2014-2024) 的791名接受937个分支PCI的患者的回顾性分析.
- 患者特征,V-RESOLVE分数和SBO.患者和无SBO.患者之间的手术结果的比较.
- 对V-RESOLVE分数四分之一和确定的截止值中SBO利率的分析.
主要成果:
- 整体SBO发生率为13%.
- 经历SBO的患者的V-RESOLVE得分更高 (中位数为16比12),增加了对斑块修饰的需求,以及更高的转化率到两种支架策略.
- V-RESOLVE得分显示了适度的预测性能,SBO的曲线下的面积 (AUC) 为0.61.
结论:
- 在PROGRESS-BIFURCATION注册表中,V-RESOLVE得分对SBO具有适度的预测价值.
- 虽然较高的分数与增加的SBO风险和程序复杂性有关,但该分数的整体区分能力有限.
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