在乙型肝炎病毒相关的肝癌中营养风险指数:感染预测和预后
Xue-Zhen Zhai1, Meng-Yun Dong1, Yi-Fan Ding1
1Department of Infectious Disease, The Fifth People's Hospital of Huai'an, Huai'an 223001, Jiangsu Province, China.
World journal of gastrointestinal oncology
|July 23, 2025
概括
营养风险指数 (NRI) 准确预测B型肝炎病毒 (HBV) 相关的肝癌患者的术后感染和预后. 该指数有助于评估感染严重程度和手术后患者的结果.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 手术瘤学手术瘤学
- 传染性疾病 传染性疾病
背景情况:
- 针对原发性肝癌的外科手术旨在降低感染风险.
- 准确预测术后并发症对于及时管理至关重要.
- 乙型肝炎病毒 (HBV) 感染是原发性肝癌的重要危险因素.
研究的目的:
- 评估营养风险指数 (NRI) 的预测和预后能力,用于与HBV相关的肝癌患者.
- 确定NRI和术后感染之间的关联,包括手术部位感染 (SSI) 和感染严重程度.
- 评估NRI在这些患者的预后评估中的作用.
主要方法:
- 分析了96名与HBV相关的初级肝癌患者进行手术的队列.
- 患者根据感染状况 (感染者与非感染者) 和感染严重程度 (轻度与严重程度) 进行分类.
- 在不同组中比较了NRI,并使用接收器操作特征 (ROC) 曲线分析评估了SSI,感染严重程度和预后的预测值.
主要成果:
- 与轻度感染患者相比,患有严重感染的患者的NRI值明显较低 (P <0.05).
- 与预后不佳的患者相比,预后良好的患者的NRI显著较低 (P <0.05).
- ROC分析表明,NRI在预测SSI (AUC=0.984),感染严重程度 (AUC=0.986) 和患者预后 (AUC=0.949) 中具有很高的准确性.
结论:
- 营养风险指数 (NRI) 作为手术后手术部位感染 (SSI) 的可靠预测指标,用于与HBV相关的肝癌.
- 在评估术后感染的严重程度和为患者提供预后见解方面,NRI是有价值的.
- 这些发现支持将NRI评估纳入手术中HBV相关肝癌患者的管理.
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