简化单剂量包装处理流程提高了在药物发行时的运营效率:一项回顾性研究.
Takahiro Kato1,2, Miki Kato1, Kazuyo Nagashiba1
1Department of Pharmacy, Aichi Medical University Hospital, 1-1 Yazakokarimata, Nagakute city, Aichi 480-1195, Japan.
Exploratory research in clinical and social pharmacy
|July 23, 2025
概括
优化一次剂量包 (ODP) 验证工作流程显著减少了医院药房发行时间. 这一策略在不增加药剂师工作量的情况下提高了效率,证明了简化流程的影响.
科学领域:
- 药房实践 在药房实践.
- 医疗保健服务研究 医疗服务研究
- 药物分配效率提高了药物分配效率.
背景情况:
- 日本药剂师试图通过流程简化和协议开发来提高效率和沟通.
- 虽然自动化分发系统显示出希望,但它们对药房效率的影响的经验数据仍然有限.
- 这项研究调查了影响药剂师在药品发行业务效率的关键因素.
研究的目的:
- 确定影响药剂师在医院环境中的药剂发行时间的因素.
- 评估实施工作流程优化策略对分配效率的影响.
- 确定是否可以在不改变员工数量的情况下实现效率提升.
主要方法:
- 对连续两年 (2020-2022) 的每日医院药房报告的回顾性分析.
- 主要结局指标是药物发放的平均持续时间.
- 采用多重回归分析来确定影响发行时间的重要因素,然后进行干预和结果评估.
主要成果:
- 处方/药剂师比例,单剂量包 (ODP) 处方的数量和粉末药物的处理是影响发行时间的重要因素.
- 实施优化的ODP验证工作流导致平均发药时间显著减少 (20.0 ± 4.0分钟到18.5 ± 3.6分钟).
- 干预后,在20分钟内完成任务的比例从56.3%增加到73.6%,表明效率提高.
结论:
- 简化一次剂量包 (ODP) 验证流程是提高医院药房配药效率的关键策略.
- 工作流的优化可以减少分配时间,增加任务完成率,而无需改变员工.
- 建议进行进一步的多中心研究,以在不同的医疗保健机构中验证这些发现.
相关概念视频
Dosage Regimen: Fixed Dose
2.0K
Fixed-dose regimens are a common approach to administer drugs to achieve and maintain desired levels of the drug in the body. In this dosing strategy, a specific amount of medication is given at regular intervals, often multiple times a day, to ensure a consistent drug concentration in the bloodstream.
Fixed-dose regimens can be used for various routes of administration, including intravenous (IV) injections and oral medications. For IV administration, a predetermined amount of the drug is...
Fixed-dose regimens can be used for various routes of administration, including intravenous (IV) injections and oral medications. For IV administration, a predetermined amount of the drug is...
2.0K
Drug Distribution as One-Compartment Model and Elimination by Nonlinear Pharmacokinetics: Overview
124
Drug administration can occur through various routes, each of which may result in a different process of elimination. This process is often mixed with nonlinear and linear processes. It's important to understand that a single drug can be metabolized into different metabolites through parallel processes.
For instance, consider the metabolism of sodium salicylate. This compound is metabolized into two distinct substances: a glucuronide and a glycine conjugate. The rate of conjugation depends...
For instance, consider the metabolism of sodium salicylate. This compound is metabolized into two distinct substances: a glucuronide and a glycine conjugate. The rate of conjugation depends...
124
One-Compartment Open Model for IV Bolus Administration: Estimation of Elimination Rate Constant, Half-Life and Volume of Distribution
509
The one-compartment open model is a simplified approach used in pharmacokinetics to understand the distribution and elimination of a drug administered through an intravenous bolus. This model assumes rapid drug dispersal throughout the body and elimination using a first-order process. Key pharmacokinetic parameters, such as the elimination rate constant (k), half-life (t1/2), and the apparent volume of distribution (Vd), can be estimated from this model. The elimination rate is calculated...
509
Drug Delivery: Miscellaneous Routes
468
Drug delivery methods like oral inhalation, nasal sprays, transdermal patches, eye drops, intravitreal injection, and rectal administration provide localized effects with reduced toxicity.
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
Transdermal patches transport drugs...
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
Transdermal patches transport drugs...
468
One-Compartment Open Model for IV Bolus Administration: General Considerations
318
The one-compartment model is a pharmacokinetic tool that models the body as a single, uniform compartment, facilitating the understanding of drug distribution and elimination. This model is particularly beneficial for intravenous (IV) bolus administration, where the drug rapidly circulates throughout the body.
The drug's presence in the body is defined by an equation representing the difference between the rates of drug entry and exit. Key parameters—elimination rate constant,...
The drug's presence in the body is defined by an equation representing the difference between the rates of drug entry and exit. Key parameters—elimination rate constant,...
318
Biopharmaceutics and Pharmacokinetics: Overview
2.6K
Understanding drugs, drug products, and their performance in pharmaceutical science is pivotal. Drugs, whether simple molecules or complex compounds, are designed to interact with the body's biological systems to diagnose, treat, or prevent diseases. Drug products include various delivery systems such as tablets, capsules, injections, and inhalers. The performance of these drug products is gauged by their ability to deliver the active ingredient to the desired site of action at the...
2.6K


