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Updated: Sep 14, 2025

Assays for Validating Histone Acetyltransferase Inhibitors
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基于quinazoline-triazole的新型N-hydroxybenzamides/N-hydroxypropenamides作为HDAC抑制剂:设计,合成,生物评估和对接研究

Nguyen Phuong Dung1, Hwa Kyung Kim2, Nguyen Thi Nga1

  • 1Hanoi University of Pharmacy 13-15 Le Thanh Tong Hanoi Vietnam namnh@hup.edu.vn anhdt@hup.edu.vn +84-4-39332332 +84-4-39330531.

RSC advances
|July 23, 2025
PubMed
概括

针对希斯脱乙酶 (HDAC) 的新型胺酸显示出强大的抗癌活性. 某些N-基胺和N-基胺衍生物有效抑制HDAC和癌细胞生长,一些化合物对癌细胞具有显著的选择性.

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