关于从脑死亡已故捐赠者移植器官的可行性,ISOT的立场声明:德尔菲共识

关于从脑死亡已故捐赠者移植器官的可行性,ISOT的立场声明:德尔菲共识

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Manish R Balwani¹, Vivek B Kute², Jigar Shrimali³

¹Department of Nephrology, Saraswati Kidney Care Center, Nagpur and Jawaharlal Nehru Medical College (JNMC), Datta Meghe Institute of Higher Education and Research(DMIHER), Wardha, Maharashtra, India.

The Lancet regional health. Southeast Asia

|July 23, 2025

概括

印度面临着器官短缺问题,经常会抛弃脑死亡已故捐赠者 (DBDs) 的可活性器官. 该共识提供了在复杂情况下利用DBDs器官的指导,旨在扩大捐赠和改善移植获取.

科学领域:

医学科学医学科学医学科学
移植移植移植移植
公共卫生公共卫生

背景情况:

器官短缺是印度移植的一个重要障碍.
在复杂的临床场景中,由于对捐赠者适合性的担忧,脑死亡已故捐赠者 (DBDs) 的可活器官经常被丢弃.

研究的目的:

制定一个共识声明,指导移植专业人员关于DBDs器官捐献的可行性.
解决复杂或边缘捐赠者情况中使用DBD器官的挑战.
扩大DBD捐赠者库并改善亚洲的移植机会.

主要方法:

由印度器官移植学会 (ISOT) 国家专家召开的德尔菲共识进程.
根据临床背景和现有证据制定19项共识建议.
包括诸如极端年龄,并发病,感染和手术异常等情景.

主要成果:

该共识为评估不同供体情况中的器官活力提供了实际建议.
它涉及特定的临床背景,包括急性损伤,各种感染 (HCV,HBV,HIV,TB),恶性瘤,糖尿病和高血压.
该声明承认印度特定数据的局限性和与西方环境的差异.

结论:

该共识旨在优化DBDs的器官利用,特别是在具有挑战性的情况下.
它作为重症监护和移植团队的实际参考工具.
强调结构化评估,道德原则和知情同意,以加强印度和亚洲的已故捐赠者器官移植 (DDOT).

关键词:

急性损伤是什么?急性损伤是什么?已故的捐赠者已死亡最终阶段的器官衰竭是指器官衰竭的最后阶段.感染感染感染移植脏的情况

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