运动强度和糖尿病末期病风险:一项全国性基于人口的研究
Eun Hui Bae1, Sang Yup Lim2, Bong-Seong Kim3
1Department of Internal Medicine, Chonnam National University Medical School, Gwangju 61469, South Korea.
World journal of diabetes
|July 23, 2025
概括
糖尿病持续时间较长会增加末期病 (ESRD) 的风险. 然而,高强度运动可以显著降低这种风险,强调运动.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
背景情况:
- 糖尿病是末期病 (ESRD) 的主要原因之一.
- 运动是管理DM等慢性疾病的关键组成部分.
- 欧洲退休和发展计划 (ESRD) 构成了重大的公共卫生挑战.
研究的目的:
- 检查运动强度,DM持续时间和ESRD发病率之间的关联.
- 为了确定运动是否可以减轻糖尿病患者的ESRD风险.
主要方法:
- 从韩国国家卫生查 (2015-2016) 中对2,495,031名患有DM的个体进行了回顾性队列研究,后续调查至2022年.
- 考克斯的比例危险模型被采用,调整了诸如年龄,性别,收入,吸烟和并发症等混因素.
- 分析的重点是运动强度 (MET-min/week) 和DM持续时间 (年).
主要成果:
- 糖尿病持续时间较长 (≥10年) 与ESRD风险较高显著相关 (HR:2.624).
- 增加运动强度在所有DM持续时间组中都显示出对ESRD的保护作用 (最高类别HR:0.837).
- 运动的益处在非高血压,非吸烟者,酒精消耗较低,BMI较高 (≥25) 和没有蛋白尿或慢性病的人群中更为明显.
结论:
- 长时间的糖尿病持续时间是ESRD的危险因素.
- 高强度运动可以作为保护因素,减轻糖尿病患者的ESRD风险.
- 促进定期运动对于管理糖尿病和预防脏并发症至关重要.
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