联合抵抗和有氧运动对2型糖尿病的干预效应:一个元分析
Jiang-Chen Ma1,2, Song Shu3, Tian-Xiao Chen4
1Department of Geriatrics, The Affiliated Hangzhou First People's Hospital Chengbei Campus, School of Medicine, Westlake University, Hangzhou 310000, Zhejiang Province, China.
World journal of diabetes
|July 23, 2025
概括
联合抵抗和有氧运动显著改善了2型糖尿病 (T2DM) 患者的血糖和脂质谱. 与单独的有氧运动相比,这种运动方法在代谢控制和心血管风险降低方面提供了更好的好处.
科学领域:
- 内分泌学和新陈代谢学
- 运动生理学 运动生理学
- 公共卫生 公共卫生
背景情况:
- 2型糖尿病 (T2DM) 是一个全球性健康挑战,发病率很高,特别是在中国.
- 由于它与胰岛素抵抗,胰腺B细胞功能受损和代谢失调有关,T2DM管理至关重要.
- 运动治疗是糖尿病管理的关键组成部分,有望改善血糖控制.
研究的目的:
- 评估联合抵抗和有氧运动干预措施对T2DM患者血糖控制的疗效.
- 评估联合运动对主要代谢指标的影响,包括脂质概况.
- 探索综合运动策略在综合糖尿病管理中的应用.
主要方法:
- 从PubMed,EMBASE,Cochrane图书馆和中国数据库中对随机对照试验 (RCT) 的系统文献搜索.
- 纳入标准:年龄≥18岁,患有T2DM的参与者,进行了≥8周的联合抵抗和有氧运动的干预.
- 主要结局:空腹血糖,LDL-C,HDL-C,TG,HbA1c和TC. 使用RevMan软件进行的元分析.
主要成果:
- 分析了6项涉及366名参与者的RCT.
- 与空气运动单独相比,联合运动显著改善了禁食血糖,降低了LDL-C和TG,增加了HDL-C.
- 总胆固醇 (TC) 显著降低;然而,在联合和有氧运动组之间没有发现HbA1c的显著差异.
结论:
- 联合抵抗和有氧运动干预措施显示,T2DM患者的禁食血糖和脂质样本 (LDL-C,HDL-C,TG,TC) 显著改善.
- 与单独的有氧运动相比,这种运动模式在血糖控制和心血管风险管理方面显示出更好的结果.
- 运动干预措施的有效性可能会因患者年龄,基线葡萄糖水平和运动强度等因素而改变.
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