由肠道微生物群协调的1型干扰素信号抑制与维生素D3信号相关的IgE介导过敏反应

Bangtao Chen1, Tingting Song2, Fei Hao2

  • 1Department of Dermatology, Chongqing University Three Gorges Hospital, School of Medicine, Chongqing University, Chongqing, 404100, People's Republic of China.

概括

1型干扰素 (IFN1) 稳态对于通过维持维生素D3 (VD3) 水平来限制系统性过敏反应 (SA) 是至关重要的. 减少的肠道细菌体破坏了这个IFN1/VD3轴,增加了IGE的产生和SA的严重程度.

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