饮食对炎症性肠病风险的影响:系统性审查,元分析和预防方面的影响
Antoine Meyer1,2,3, Manasi Agrawal4,5,6, Einat Savin-Shalom4
1Service de Gastroentérologie, University Hospital of Bicêtre, Assistance Publique-Hôpitaux de Paris, Le Kremlin Bicêtre, France.
EClinicalMedicine
|July 23, 2025
概括
富含炎症性食物和超加工物品的饮食增加了克罗恩氏病的风险. 相反,高纤维,地中海和健康饮食与较低的克罗恩病风险有关. 性结肠炎的相关性仍然不清楚.
科学领域:
- 胃肠病学和营养科学 胃肠病学和营养科学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 关于炎症性肠病 (IBD) 的饮食风险因素,存在不一致的数据.
- 炎症性肠病 (IBD) 包括克罗恩病 (CD) 和性结肠炎 (UC).
研究的目的:
- 系统地审查和元分析有关饮食和IBD亚型之间的关系的现有数据.
- 澄清特定饮食模式对患克罗恩病和性结肠炎的风险的影响.
主要方法:
- 按照PRISMA指南进行系统的文献审查.
- 使用随机效应模型进行前性队列研究的元分析.
- 包括2025年5月8日之前从主要数据库 (Ovid Medline,Embase,Scopus) 发表的研究.
主要成果:
- 炎症饮食和超加工食品与克罗恩病 (CD) 的风险增加有关.
- 高纤维摄入量,地中海饮食,健康饮食和未加工食品与降低CD风险有关.
- 对于性结肠炎 (UC) 风险,没有发现一致的饮食相关性.
结论:
- 饮食模式显著影响发展克罗恩病的风险.
- 需要进一步的研究来了解饮食与性结肠炎的联系.
- 结果可以为IBD的预防试验和公共卫生策略提供信息.
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