美国与阿片类药物相关的医院利用趋势的变化. 成年人,2016-2021 年检查检查
Lingxiao Chen1,2,3, Zhuo Chen1, Jiaming Ding1
1Department of Orthopaedics, Qilu Hospital of Shandong University, Shandong University Centre for Orthopaedics, Advanced Medical Research Institute, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, PR China.
EClinicalMedicine
|July 23, 2025
概括
与阿片类药物相关的住院病例在2016-2021年间有显著的变化,过量服用和感染的数量增加,特别是在大流行期间. 需要针对不同类型的阿片类药物和不同患者群体量身定制的公共卫生战略.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 医疗保健服务研究 医疗服务研究
背景情况:
- 与阿片类药物相关的医院利用趋势对于公共卫生政策至关重要.
- 现有的研究往往缺乏范围和方法的深度.
- 2016-2021年国家估计显示了阿片类型和亚种群的趋势变化.
研究的目的:
- 提供2016年至2021年与阿片类药物相关的医院利用趋势的国家估计.
- 检查不同类型的阿片类药物和人口统计学子群体的趋势.
- 通过详细说明使用模式,为公共卫生政策提供信息.
主要方法:
- 使用国家住院患者样本 (NIS) 和全国急诊室样本 (NEDS) 进行重复的横截面分析.
- 对2016-2019年和2019-2021年 (COVID-19大流行期间) 进行的分析.
- 结果包括与阿片类药物相关的诊断,非致命的过量服用,注射药物使用相关的急性感染和药物滥用治疗,按阿片类别和人口统计学分析.
主要成果:
- 从2016年到2019年,NIS显示诊断,过量服用和治疗率下降,但感染率增加;NEDS显示没有显著变化. 与芬太尼相关的过量服用和海洛因中毒在特定群体中增加.
- 从2019-2021年,NIS和NEDS都显示了非致命的阿片类药物过量剂量率的增加. 尼斯也显示了注射药物使用相关的感染增加.
- 在各个人口亚组中观察到趋势的显著变化,表明了差异性的影响.
结论:
- 与阿片类药物相关的医院利用趋势在美国成年人中表现出显著的变化.
- 未来的政策必须仔细考虑这些不同的趋势,特别是在危机期间.
- 针对特定亚群体,阿片类药物类别和临床事件量身定制的管理策略对于有效的干预至关重要.
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