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Arvette E Mitchell1, Arpit P Patel1, Jennifer DiCandilo1

  • 1Department of Pathology and Genomic Medicine, Thomas Jefferson University Hospital, Philadelphia, PA 19107, USA.

Access microbiology
|July 23, 2025
PubMed
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这项研究纠正了先前发表的一篇文章DOI. 校正确保了科学研究和微生物学领域数据完整性的准确引用.

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Methicillin-resistant Staphylococcus aureus (MRSA) presents a critical public health threat, arising from its capacity to resist β-lactam antibiotics due to acquisition of the mecA gene within the staphylococcal cassette chromosome mec (SCCmec). This gene encodes penicillin-binding protein 2a (PBP2a), which impairs binding efficacy of methicillin and other β-lactams. MRSA has evolved into distinct clonal lineages impacting humans and animals alike, reinforcing its significance within...
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