在腹部手术中术后并发症和血清白蛋白水平之间的相关性:一项前性观察性研究
Sumeet Kumar1, Kanchan Sonelal Baitha2, Anand Dev3
1General Surgery (Trauma and Emergency), Indira Gandhi Institute of Medical Sciences, Patna, IND.
Cureus
|July 23, 2025
概括
手术前的低albuminemia,一种低血清白蛋白的状态,显著增加了手术后并发症的风险和腹部手术患者的长时间住院. 常规的白蛋白检测可以改善手术规划和患者的治疗结果.
科学领域:
- 手术瘤学手术瘤学
- 临床营养学 临床营养学
- 关键护理医学 关键护理医学
背景情况:
- 低albuminemia是营养不良和炎症的已知的指标.
- 它在手术风险分层中的作用越来越被认可,特别是在腹部手术中.
- 对于印度人群,关于手术前血清白蛋白的预测价值的前性数据有限.
研究的目的:
- 在接受腹部手术的患者中调查术前血清白蛋白水平和术后并发症之间的关联.
- 评估在印度队列中的常规临床实践中低albuminemia的预测效用.
主要方法:
- 对69名接受腹部手术的患者进行前性观察性研究.
- 在手术前测量血清白蛋白水平 (<3.5 g/dL 低白蛋白,≥3.5 g/dL 标准白蛋白).
- 统计分析包括千平方,曼-惠特尼U测试和多变量逻辑回归.
主要成果:
- 在65.2%的患者中,呈现出低albuminemia.
- 低albuminemic 患者的术后并发症发生率明显较高 (57.8%对12.5%,p < 0.001).
- 低albuminemia是并发症 (OR=12.68) 和更长的住院时间 (10.1 和 6.9 天) 的独立预测因素.
结论:
- 手术前的低albuminemia是术后并发症和腹部手术后长时间住院的强大,独立的预测因素.
- 建议进行常规的术前血清白蛋白评估,以更好地进行术后规划和优化结果.
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