在多哥的风患者中,与细菌感染相关的流行和因素
Laté Mawuli Lawson-Ananissoh1,2, Mawunyo Henoc Gbolou1, Debehoma Venceslas Redah1
1Hepato Gastroenterology Department, Campus Teaching Hospital, Lome, Togo.
Arquivos de gastroenterologia
|July 23, 2025
概括
细菌感染影响了多哥近四分之一的肝硬化患者,炎和肝脏脑病是关键的危险因素. 这些感染与高死亡率有关,这强调了晚期肝硬化需要主动治疗的必要性.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 传染性疾病 传染性疾病
- 临床研究 临床研究
背景情况:
- 细菌感染是肝硬化患者常见和严重的并发症.
- 这些感染经常与诸如炎,肝脏脑病变和MELD得分升高等疾病有关.
- 自发性细菌腹膜炎和尿路感染是观察到的最常见类型.
研究的目的:
- 确定多哥的肝硬化患者中细菌感染的流行率.
- 在这个患者群体中识别与细菌感染相关的因素.
主要方法:
- 一个描述性和分析性的横截面研究,与回顾性数据收集.
- 在校园大学医院的肝胃肠病学部门进行了三年.
- 包括所有在研究期间被诊断为肝硬化住院的患者.
主要成果:
- 在270名肝硬化患者中,细菌感染的患病率为23.3%.
- 最常见的是自发性炎液感染 (15.9%) 和尿路感染 (4%).
- 相关因素包括炎 (OR=4.56),肝脏脑病变 (OR=4.32),低血栓激素水平 (OR=9.67) 和高MELD得分 (OR=0.93).
- 感染患者的死亡率为57.1%.
结论:
- 细菌感染是晚期肝硬化的一个重要并发症.
- 细菌感染的存在与肝硬化患者的预后不佳有关.
- 这些发现强调了在这个易受伤害的群体中早期检测和管理细菌感染的必要性.
相关概念视频
Factors Affecting the Risk of Infection
12.3K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
12.3K
Diseases of the Liver and Gallbladder
1.0K
Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
1.0K
Pulmonary Tuberculosis I
329
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
329
Gastritis III: Clinical Manifestations and Management
484
The clinical manifestations of gastritis can vary depending on the cause and type of gastritis, but some common symptoms may include the following.
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
484
Gastritis-II: Pathophysiology
558
Gastritis is marked by disruption of the mucosal barrier that usually protects the stomach tissue from digestive juices and manifests in acute and chronic forms.
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
558
Esophageal Varices-II: Clinical Features and Management
145
Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
145


