为慢性重症患者提供鼓舞人心的肌肉训练:随机对照试验的系统审查和元分析
Gustavo Rodrigues das Chagas1, Aléxia Gabriela da Silva Vieira1, Jamile Caroline Garbuglio de Araújo1
1Hospital Israelita Albert Einstein, São Paulo, SP, Brazil.
Einstein (Sao Paulo, Brazil)
|July 23, 2025
概括
启发性肌肉训练可能会增强严重病情的成年人的启发性肌肉力量,但证据质量非常低. 它对通风持续时间或不良事件的影响很小,对死亡率的影响不确定.
科学领域:
- 关键护理医学 关键护理医学
- 呼吸系统生理学 呼吸系统生理学
- 康复科学 康复科学 康复科学
背景情况:
- 危急病患者经常经历呼吸道肌肉衰弱,影响恢复和结果.
- 鼓舞性肌肉训练 (IMT) 是一个潜在的干预措施来解决这个弱点.
研究的目的:
- 系统地审查和分析IMT在成年慢性重症患者的疗效和安全性的研究.
主要方法:
- 在多个数据库 (MEDLINE,Embase等) 进行了搜索. 在2025年1月之前.
- 包括7项涉及390名参与者的研究,分析了诸如呼吸肌肉强度和机械通风持续时间等主要结果.
- 使用RevMan V5.4用于按照PRISMA指南进行统计分析.
主要成果:
- IMT显示,与通常护理相比,灵感肌肉强度显著增加 (证据确定性非常低).
- 与假冒干预相比,没有观察到强度的显著差异 (证据确定性非常低).
- 肺功能,通风持续时间和死亡率的结果不准确,证据确定性非常低.
结论:
- IMT可以改善吸气肌的强度,对通风持续时间和不良事件的影响最小.
- 对所有结果的证据确定性非常低.
- IMT对重症监护室死亡率和停留时间的影响仍然不确定.
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