菌细菌的存活性保护被封装在素强化pH响应复合酸水凝基质基质中,作为共生传递系统
Souptik Bhattacharya1, Sanjana Baidya2
1Department of Food Technology, Guru Nanak Institute of Technology, Kolkata, 700114, West Bengal, India. souptikjduv@gmail.com.
Probiotics and antimicrobial proteins
|July 23, 2025
概括
这项研究开发了复合水凝,以保护像Alkalihalobacillus clausii和Lactobacillus plantarum这样的益生菌. 生物膜载荷的水凝对处理和消化应激的生存能力有所提高,这表明它是一个有前途的共生传递系统.
科学领域:
- 生物材料科学 生物材料科学
- 微生物学 微生物学
- 食品科学 食品科学 食品科学
背景情况:
- 益生菌的生存能力是消化保健产品面临的主要挑战.
- 开发有效的输送系统对于益生菌的有效性至关重要.
- 类杆菌 (Alkalihalobacillus clausii) 和乳杆菌 (Lactobacillus plantarum) 是关键的益生菌物种.
研究的目的:
- 为了创建多糖体增强的复合水凝,用于益生菌封装.
- 为了提高益生菌细胞 (Alkalihalobacillus clausii和Lactobacillus plantarum) 在加工和胃肠道过境期间的生存和稳定性.
- 评估水凝对浮游生物和生物膜类型益生菌细胞的保护作用.
主要方法:
- 用于制备水凝的离子凝方法.
- 响应表面优化,以提高封装效率和细胞活力.
- 在各种压力条件下 (热,结,pH,储存) 评估益生菌的生存能力.
- 对抗大肠杆菌的抗菌活性的评估.
主要成果:
- 生物膜装载的水凝显示出优越的抗酸性和长期可行性.
- 在生物膜加载的水凝中观察到高达70°C的增强耐热性.
- 生物膜细胞在模拟的肠液中保持了更长的活力,尽管释放率较低.
- 益生菌提取物和秘密体显示出对致病性大肠杆菌具有显著的抗菌作用.
结论:
- 补充了pectin的alginate珠作为一个有效的共生传输系统.
- 生物膜封装显著提高了益生菌对加工和消化应激的弹性.
- 开发的水凝为基于益生菌的药物和营养产品提供了有希望的方法.
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