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Updated: Sep 14, 2025

Author Spotlight: Combining Proximity Ligand Assay with Gamma-H2AX Staining to Characterize Protein Interactions in DNA Damage Response
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Published on: August 2, 2024

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克鲁佩尔样因子4缺乏的细胞对乙化物诱导的DNA损伤敏感

Maxwell H Rubinstein1, Aidan Conroy1,2, Elisabeth L Pezzuto1,3

  • 1Department of Biology, Colgate University, Hamilton, NY 13346, USA.

Current issues in molecular biology
|July 23, 2025
PubMed
概括

克鲁佩尔样因子4 (KLF4) 增强了DNA损伤的修复,并保持了遗传稳定性. 这种转录因子上调调节DNA损伤反应基因,支持其作为瘤抑制剂的作用.

关键词:
造成的DNA损伤是DNA损伤.对DNA损伤的反应反应修复DNA的修复DNA的修复克鲁佩尔的类似因素4细胞循环中的细胞循环.基因组的不稳定性

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