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Alisa K Molina¹, Helen Tasho¹, Yameng Ge²

¹Clinical Research Center, Herbert Wertheim School of Optometry and Vision Science, University of California, Berkeley, California.

Optometry and vision science : official publication of the American Academy of Optometry

|July 23, 2025

概括

没有症状的软隐形眼镜佩戴者,眼水分产生率 (TAP) 较低. 然而,有症状的佩戴者表现出更高的TAP率,这表明透镜如何根据佩戴者的经验影响眼产生的差异.

科学领域:

眼科医生眼科眼科
眼睛表面疾病眼睛表面疾病
隐形眼镜技术隐形眼镜技术

背景情况:

水生成率 (TAP) 是眼睛舒适和健康的关键因素.
了解软隐形眼镜 (CL) 佩戴者的TAP速率变化对于诊断和管理干眼疾病至关重要.
以前的研究表明,CL磨损与改变膜动态之间存在联系.

研究的目的:

调查TAP率在症状和无症状软CL佩戴者中的作用.
为了在四个不同的群体中比较TAP率:症状的CL佩戴者与干眼,症状的CL佩戴者与隐形眼镜引起的干眼,无症状的CL佩戴者和无症状的非CL佩戴者.

主要方法:

用伯克利干眼流图对受试者进行了分类.
使用修改后的 (覆盖的) 希尔默条纹试验量化了TAP率.
数据分析涉及一个线性混合模型,考虑混因素和随机效应.

主要成果:

无症状的CL佩戴者表现出最低的平均TAP速率 (1.2μL/分钟).
与无症状的CL佩戴者相比,无症状的非CL佩戴者,隐形眼镜诱导的干眼和干眼组在早上显示出明显更高的TAP率.
这些差异表明,习惯性CL穿戴可能会降低TAP率.

结论:

与非佩戴者相比,无症状的软CL佩戴与TAP率降低有关.
有症状的CL佩戴者表现出比无症状佩戴者更高的TAP率.
需要进一步调查,以区分症状组之间的TAP率,并了解CL相关的不适机制.

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