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Updated: Sep 14, 2025

An Oncogenic Hepatocyte-Induced Orthotopic Mouse Model of Hepatocellular Cancer Arising in the Setting of Hepatic Inflammation and Fibrosis
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免疫疗法在胃肠道癌症:从关键试验和未来临床应用的教训

Supriya Peshin1, Faizan Bashir2, Naga Anvesh Kodali3

  • 1Norton Community Hospital, Ballad Health, Norton, VA 24273, USA.

Antibodies (Basel, Switzerland)
|July 23, 2025
PubMed
概括

免疫疗法在胃肠道癌症中表现有前途,特别是针对不匹配修复缺陷瘤的免疫检查点抑制剂 (ICI). 然而,在其他亚型中,耐药性和有效性有限等挑战需要进一步研究生物标志物和组合策略,以改善结果.

关键词:
在PD-1/PD-L1路径上.胃肠道的癌症,胃肠道的癌症.免疫检查点抑制剂 (ICI)免疫疗法 免疫疗法微卫星不稳定性高 (MSI-H) 缺陷不匹配修复 (dMMR)

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