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Updated: Sep 14, 2025

Medium-throughput Screening Assays for Assessment of Effects on Ca2+-Signaling and Acrosome Reaction in Human Sperm
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Medium-throughput Screening Assays for Assessment of Effects on Ca2+-Signaling and Acrosome Reaction in Human Sperm

Published on: March 1, 2019

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综合性因果和单细胞分析揭示了对导致人类男性不孕症的内分泌干扰剂反应的基因

Yanggang Hong1, Yirong Wang2, Jiajun Li2

  • 1Key Laboratory of Structural Malformations in Children of Zhejiang Province, Department of Pediatric Urology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China; Key Laboratory of Children Genitourinary Diseases of Wenzhou City, Department of Pediatric, Urology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical, University, Wenzhou, Zhejiang, China; Wenzhou Medical University, Zhejiang, China.

Ecotoxicology and environmental safety
|July 23, 2025
PubMed
概括

环境化学物质通过改变丸细胞中的基因表达来破坏男性的生育能力. 这项研究确定了六个关键基因与男性不孕症和环境暴露有因果关系,为分子机制提供了洞察力.

关键词:
化学基因协会 化学基因协会破坏内分泌的化学物质 破坏内分泌的化学物质环境因素 环境因素男人不孕不育的情况门德尔的随机化

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