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Updated: Sep 14, 2025

Establishment of a High-throughput Setup for Screening Small Molecules That Modulate c-di-GMP Signaling in Pseudomonas aeruginosa
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抗微生物药物中的一个灰娘故事:CDPDP非常适合多途径细菌抑制

Syed Shams Ul Hassan1, Naveed Ahmad2, Abdur Rehman3

  • 1Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, School of Pharmacy, Shanghai Jiao Tong University, Shanghai, 200240, China.

European journal of medicinal chemistry
|July 23, 2025
PubMed
概括

海洋化合物CDPDP显示出强大的抗菌活性,可以对抗金黄色葡萄球菌和Riemerella anatipestifer. 它向S. aureus中的DNA复制,并破坏R. anatipestifer中的膜,提供潜在的宽谱抗生素.

关键词:
有抗菌作用的抗菌剂.作用机制 作用机制分子对接是分子对接.R. 没有比虫更害虫.我们的S.aureus.转录组 转录组就是一个转录组.

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