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Updated: Sep 14, 2025

Detection of Alternative Splicing During Epithelial-Mesenchymal Transition
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CK1ε/SRSF10轴调节肺癌细胞中Bcl-x的替代拼接

Qi Sun1, Yun Tang1, Lian Wang2

  • 1Guangdong Provincial Key Laboratory of Regional Immunity and Disease, International Cancer Center, Marshall Laboratory of Biomedical Engineering, Department of Pharmacology, Shenzhen University Medical School, Shenzhen University, Shenzhen, Guangdong, China; School of Pharmacy, Shenzhen University Medical School, Shenzhen University, Shenzhen, Guangdong, China.

The Journal of biological chemistry
|July 23, 2025
PubMed
概括

氨酸激酶1ε (CK1ε) 通过酸化SRSF10.0来调节Bcl-x的替代拼接. 这种CK1ε/SRSF10通路是抑制肺癌生长和化学抵抗的潜在治疗标.

关键词:
在 Bcl-x 中,在CK1ε.在SRSF10中,我们可以使用SRSF10.替代性拼接是一种替代性的拼接.肺癌是一种肺癌.

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