过敏性排骨炎后过敏性疾病的长期风险:临床视角
Alp Kazancioglu1, Cansu Ozdemiral1, Pinar Gur Cetinkaya1
1Pediatric Allergy Department, Hacettepe University School of Medicine, Ankara, Turkey.
概括
患有食物蛋白诱导过敏性口腔炎 (FPIAP) 的儿童面临患喘和过敏性鼻炎 (AR) 的风险更高. 持续监测对于这些孩子来说至关重要,以管理他们的长期过敏状况.
科学领域:
- 儿科过敏和免疫学
- 胃肠病学 胃肠病学
- 临床研究 临床研究
背景情况:
- 长期的过敏结果对于有食物蛋白诱导过敏直肠炎 (FPIAP) 病史的儿童是不确定的.
- 了解FPIAP后过敏状况的进展对于有效的患者管理至关重要.
研究的目的:
- 确定过敏性疾病的患病率和临床特征,特别是喘和过敏性鼻炎 (AR),在有FPIAP病史的儿童中.
- 将FPIAP患者患喘和AR的风险与具有不同过敏史的对照组进行比较.
主要方法:
- 一项回顾性病例控制研究包括了170名被诊断患有FPIAP的患者.
- 对照组包括非食物过敏 (非FA) 患者,已经过长的IgE介导牛奶过敏 (IgE-CMA) 和当前的IgE-CMA.
- 喘和AR的比例在FPIAP和对照组之间进行了比较.
主要成果:
- 与非FA组相比,有FPIAP病史的患者患喘 (aOR: 4.273) 和AR (aOR: 3.039) 的风险显著更高.
- 喘 (45.2%) 和AR (17.6%) 的患病率在FPIAP组中高于非FA组 (分别为12.9%和5.9%).
- 与IgE介导牛奶过敏患者相比,FPIAP组的喘控制较差.
结论:
- 患有FPIAP病史的儿童患喘和过敏性鼻炎的风险增加.
- 这些发现强调了需要继续监测和监测有FPIAP病史的儿童的过敏状况.
- 需要进一步的研究来阐明FPIAP在过敏过程的更广泛背景中的作用.
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