在食物传播疾病中的益生菌和益生菌:机制,应用和未来方向
Louise Iara Gomes de Oliveira1, Ana Rita Ribeiro de Araujo2, Tatiana Colombo Pimentel3
1Laboratory of Microbial Processes in Foods, Federal University of Paraíba, João Pessoa, Brazil.
Journal of food protection
|July 23, 2025
概括
益生菌和益生菌显示出作为抗生素替代品的承诺,用于预防和治疗食物传播疾病 (FBDs). 这些有益的微生物及其基质通过各种机制增强肠道健康并对抗病原体.
科学领域:
- 微生物学 微生物学
- 公共卫生 公共卫生
- 胃肠病学 胃肠病学
背景情况:
- 食物传播疾病 (FBD) 是一个重要的全球健康问题,导致广泛的疾病,住院和死亡.
- 抗生素耐药性需要探索用于管理FBDs的替代策略.
- 益生菌和益生菌因其潜在的健康益处和调节肠道微生物组的作用而得到认可.
研究的目的:
- 审查和分析用于预防和治疗FBDs益生菌和益生菌的证据.
- 阐明益生菌和益生菌对食品传播病原体施加保护作用的机制.
- 探索益生菌和益生菌作为FBD常规抗生素治疗的替代品或辅助剂的潜力.
主要方法:
- 这篇迷你综述综合了关于益生菌,益生菌和FBDs的现有科学文献.
- 分析了来自体外,体内和人体研究的证据.
- 研究了作用机制,包括抗微生物物质的产生,免疫调节和肠道屏障增强.
主要成果:
- 益生菌通过产生抗微生物化合物,调节免疫力和减少病原体负载来证明对病原体的有效性.
- 益生菌促进有益细菌,增加短链脂肪酸 (SCFA) 生产,并增强肠道屏障功能.
- 益生菌和益生菌都能抑制病原体的粘附并调节免疫反应.
结论:
- 益生菌和益生菌为管理FBD提供了可行的治疗策略,通过多种机制发挥作用.
- 它们的联合使用可能会提高疗效,为抗生素治疗提供有希望的替代品或补充剂.
- 对其应用的进一步研究可以大大有助于改善与FBD相关的全球公共卫生结果.
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