在高强度运动后重复测量热素I的潜在诊断益处
I H Hove1, Ø Kleiven2, M F Bjørkavoll-Bergseth3
1Department of Cardiology, Stavanger University Hospital, Norway; University of Bergen, Norway.
与没有 (Wo-CAD) 相比,最大限度的炼使心脏托罗素I (cTnI) 在复血管化冠状动脉疾病 (Revasc-CAD) 患者中持续升高. 重复的CTnI监测可能会检测出正在发展的冠状动脉阻塞.
科学领域:
- 心脏病学 心脏病学
- 运动生理学 运动生理学
背景情况:
- 心肌压力,通过心脏托罗邦素I (cTnI) 的升高而表明,在患有或没有冠状动脉疾病的个体中,在运动后发生.
- 了解运动强度和持续时间对cTnI水平的影响对于治疗冠状动脉疾病患者至关重要.
研究的目的:
- 为了比较经过训练后的cTnI水平,在经过良好训练的患者中,有稳定的重血管化冠状动脉疾病 (Revasc-CAD) 与没有阻塞性冠状动脉疾病 (Wo-CAD) 的患者.
- 研究最大与长时间高强度运动对这些群体cTnI水平的影响.
主要方法:
- 一项观察性研究涉及15名Revasc-CAD和22名Wo-CAD个体.
- 运动前,3小时和24小时后cTnI水平的测量.
- 参与者完成了最大心肺运动测试和三次高强度间歇旋转 (20,40,60分钟).
主要成果:
- cTnI水平在运动后3小时达到峰值,并在24小时下降 (p < 0.001),60分钟会话后达到最高水平 (p = 0.001).
- 在高强度运动或增加持续时间后,在Revasc-CAD和Wo-CAD组之间没有观察到cTnI水平的显著差异.
- 与Wo-CAD组不同的是,Revasc-CAD个体在最大运动后3小时至24小时之间没有显示cTnI的减少.
结论:
- 不同持续时间的高强度运动在两组中都引起了类似的cTnI升高.
- 最大运动导致长时间的cTnI升高,特别是在Revasc-CAD组.
- 在患有静脉静脉狭窄的患者中,运动后渐进的cTnI增加表明,对检测冠状动脉阻塞进行连续cTnI评估是有用的.
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