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Updated: Sep 14, 2025

HSV-Mediated Transgene Expression of Chimeric Constructs to Study Behavioral Function of GPCR Heteromers in Mice
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药理学和遗传学证据汇聚在精神病疾病的机制上

Brian Fennessy1, Liam Cotter1, Nicole W Simons1

  • 1Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, USA.

Translational psychiatry
|July 23, 2025
PubMed
概括

这项研究通过整合药物,遗传和临床数据,揭示了特异性和物质诱导精神病的常见遗传标. GRIN2A被确定为新型精神病治疗的关键基因,提供新的治疗途径.

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