piENOX2调节ALKBH5介导的Itga4 m6 一种修改,以加速类风湿性关节炎的进展

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An Adoptive Transfer Model of Rheumatoid Arthritis in Mice
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Naibo Feng1,2, Chungeng Liu1,3, Yuan Zhu1,2

  • 1Division of Spine, Department of Orthopedic Surgery, Shenzhen People's Hospital, The Second Clinical Medical College, Jinan University; The First Affiliated Hospital, Southern University of Science and Technology, Shenzhen, China.

Experimental & molecular medicine
|July 23, 2025
PubMed
概括

与PIWI相互作用的RNA ENOX2通过促进M1巨细胞两极分化来驱动类风湿性关节炎 (RA). 抑制piENOX2可减少RA炎症和软骨损伤,为这种自身免疫性疾病提供潜在的治疗策略.

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