儿科外皮皮质冠状腺新血管化二次性眼球沙尔科毒症:一个长期随访病例
Yuan Zong1,2,3, Keyan Wang1,2,3, Ting Zhang4,5,6
1Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, 200031, China.
BMC ophthalmology
|July 23, 2025
概括
本案例研究描述了一名14岁的男孩患有眼皮型硬化症和双侧周皮状新血管化 (PCNV). 有效的管理需要多学科的方法和长期的跟进,以保护视力.
科学领域:
- 眼科医生 眼科 眼科
- 免疫学 免疫学 免疫学
- 儿科 儿科 儿科
背景情况:
- 呈现了一例罕见的14岁男性病例,可能患有眼部沙丘病.
- 突出显示,儿科患者中出现了双边周包膜胆道新血管化 (PCNV).
研究的目的:
- 描述PCNV的儿科眼部肉类瘤的临床表现和管理.
- 为了强调诊断和治疗青少年这种疾病的挑战.
主要方法:
- 一个14岁男孩的病例报告,有2个月的视力障碍史.
- 诊断工作包括眼科检查,血清 ангиотензин转化酶水平和正子发射断层扫描 (PET).
- 治疗包括免疫调节疗法和静脉内抗血管内皮生长因子 (抗VEGF) 注射.
主要成果:
- 患者表现出双边颗粒状膜炎,并出现周边状子膜病变.
- 血清 ангиотензин转化酶和PET发现的升高证实了沙尔科毒症.
- 尽管初始治疗,PCNV在左眼显示缓慢的进展,最终通过联合治疗控制.
结论:
- 患有PCNV的儿科眼部肉类瘤需要一个多学科的方法,以获得最佳的管理.
- 长期随访对于监测年轻患者的疾病进展和治疗疗效至关重要.
- 这一案例凸显了治疗儿童眼睛自身免疫性疾病的复杂性.
相关概念视频
01:27Open Angle Glaucoma: Treatment
577
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
577
01:28Angle Closure Glaucoma: Treatment
691
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
691