使用18F-氧-d-葡萄糖PET/计算机断层扫描衍生放射学来分类甲状腺附带瘤的恶性病变
Melda Yeghaian1,2, Marceline W Piek3, Annemarieke Bartels-Rutten1
1Departments of Radiology, Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam.
Nuclear medicine communications
|July 24, 2025
概括
来自PET/CT扫描的放射性特征可以帮助癌症患者区分良性与恶性甲状腺意外瘤. 这种非侵入性成像方法显示出有希望的结果,与已建立的分类相提并论.
科学领域:
- 核医学是一种核医学.
- 放射学 放射学是一门学科.
- 在瘤学瘤学.
背景情况:
- 甲状腺意外瘤 (TIs) 是18F-FDG PET/CT扫描中的常见发现.
- 鉴别这些病变对于瘤学环境中的患者管理至关重要.
研究的目的:
- 评估非侵入性PET/CT衍生的放射性特征在区分良性与恶性甲状腺偶发性瘤的有用性.
- 为了比较放射学与超声波TIRADS分类的性能.
主要方法:
- 46名PET/CTTI患者接受了超声波和手术.
- 从PET和CT图像中提取了放射性特征.
- 组织病理学作为参考标准;分析包括单变量,多变量和对TIRADS进行比较评估.
主要成果:
- 在78%的TI中发现了恶性病变.
- 一个结合的放射性特征 (运行长度不均) 实现了AUC为0.88,相当于TIRADS (AUC:0.84).
- 在多变量分析中,CT衍生放射学表明与TIRADS (AUC:0.80) 相比,CT衍生放射学具有更好的预测性能 (AUC:0.86).
结论:
- 18F-FDG PET/CT衍生放射学显示出区分良性和恶性甲状腺病变的显著潜力.
- 建议使用更大的队列和先进的方法,如深度学习,以进一步验证.
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