与连续干预相比,同时进行的干预在急性瘤性胰腺炎多个部位的感染性瘤集合中没有优势:一项随机试验
Bikkina Venkat Siddharda1, Jimil Shah1, Pankaj Gupta2
1Department of Gastroenterology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
Journal of gastroenterology and hepatology
|July 24, 2025
概括
对于多焦点采集的感染性胰腺亡 (IPN),同时干预并不优于连续干预. 顺序方法可能会减少IPN管理所需的干预次数.
科学领域:
- 胃肠病学 胃肠病学
- 干预性放射学 干预性放射学
- 手术瘤学手术瘤学
背景情况:
- 感染性胰腺亡 (IPN) 往往呈现出需要干预的多焦点收集.
- 对于多焦点IPN,同步与顺序干预的比较疗效尚不清楚.
研究的目的:
- 在患有多焦点感染性胰腺缩的患者中,比较同步与连续干预的疗效.
- 评估两种方法之间的并发症率,干预次数和死亡率.
主要方法:
- 进行了一个单中心,开放标签,随机优越性试验.
- 60名多焦点IPN患者被随机分为同时 (A组) 或顺序 (B组) 的干预组.
- 主要结果是综合并发症指数 (CCI);次要结果包括干预数量和死亡率.
主要成果:
- 同时 (72.5) 和顺序 (64.4) 组之间的平均CCI没有显著差异.
- 顺序组需要显著减少干预措施 (2.97对比4.17).
- 在不同组之间,新发器官衰竭,手术干预和死亡率的比例相似.
结论:
- 对多焦点IPN的同时干预并不优于以临床结果为指导的顺序方法.
- 连续干预可能会减少管理IPN所需的程序的总数.
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