在COPD住院后的主要不良心血管事件和特定原因死亡率
Anne E Ioannides1, Hannah R Whittaker1, Jennifer K Quint1
1School of Public Health (SPH), White City Campus, Imperial College London, London, UK.
住院治疗显著增加慢性阻塞性肺病 (COPD) 患者的心血管风险和死亡率. 这突出了在住院期间预防心血管事件的机会.
科学领域:
- 心脏病学 心脏病学
- 肺部病理学 肺部病理学
- 公共卫生 公共卫生
背景情况:
- 慢性阻塞性肺病 (COPD) 患者面临更高的心血管事件和死亡风险.
- 了解住院对这些风险的影响对于患者管理至关重要.
研究的目的:
- 调查住院和重大心血管不良事件 (MACE) 和COPD患者因特定原因死亡率的一年率之间的关系.
- 根据住院类型 (选择性或紧急) 和原因分层风险.
主要方法:
- 在英格兰 (2010-2019) 使用链接电子医疗记录的前性队列研究.
- 对住院COPD患者与非住院对照组的结果进行比较.
- 使用调整后的考克斯回归和倾向得分调整模型.
主要成果:
- 住院COPD患者的1年MACE (可选和紧急入院) 率显着更高.
- 紧急住院治疗与所有原因死亡率的增加有很强的相关性,无论原因如何.
- 选择性住院也增加了全因死亡率,除了心血管特定的入院病例.
结论:
- 由于任何原因住院的COPD患者面临MACE的风险增加和出院后的死亡率.
- 住院治疗是实施COPD患者心血管事件的初级预防策略的关键窗口.
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