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Updated: Sep 14, 2025

Generation of Genomic Deletions in Mammalian Cell Lines via CRISPR/Cas9
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Generation of Genomic Deletions in Mammalian Cell Lines via CRISPR/Cas9

Published on: January 3, 2015

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一个基于CRISPR/Cas9的系统,使用双sgRNAs来有效删除Mycobacterium的基因

Linai Li1, Yuxiang Hu1, Dan Wang1

  • 1Institute of Respiratory Health, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, China.

Frontiers in microbiology
|July 24, 2025
PubMed
概括

研究人员开发了一种CRISPR-Cas9系统,用于在Mycobacterium疹感染中大规模删除DNA. 这种工具增强了对这种具有挑战性的病原体抗药性和毒性的研究.

关键词:
克里斯普尔是什么意思?克里斯普尔是什么意思?这种细菌是Mycobacterium abscessus.双重的sgRNAss可以使用.基因组编辑 基因组编辑大片段删除大片段删除

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