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在传统中医药中的体外技术和ADMET研究

Jinhao Xue1, Shiwen Gao1, Zhibo You1

  • 1Key Laboratory of Basic and Application Research of Beiyao, Heilongjiang University of Chinese Medicine, Ministry of Education, Harbin, China.

Frontiers in pharmacology
|July 24, 2025
PubMed
概括

在体外模型为研究复杂的传统中医药 (TCM) 吸收,分布,新陈代谢,分泌和毒性 (ADMET) 提供了先进的解决方案. 这些方法可以对TCM组件及其相互作用进行详细分析.

关键词:
接收人 接收人器官在芯片上的器官在体外模型模型中的体外模型.有机生物有机物传统的中国医药传统的中国医药.

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Methods for Studying Drug Absorption: In vitro01:16

Methods for Studying Drug Absorption: In vitro

In vitro experiments are crucial for understanding the transport and absorption of drugs through biological materials. These studies employ varied methods such as the diffusion cell method, the everted sac technique, and the everted ring technique.
The diffusion cell method uses a two-compartment cell, including a donor compartment with the drug solution, which simulates the environment where the drug is applied, and a receptor compartment with a buffer solution, which simulates the environment...
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