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Updated: Sep 14, 2025

Author Spotlight: Unveiling the Role of TMOD3 in Platinum Resistance and Immune Infiltration in Ovarian Cancer
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在非小细胞肺癌中,STAT3通过调节非小细胞肺癌中的蛋白质分泌来调节CAF诱导的奥西默蒂尼布耐药性

Xuchen Fan1,2, Sheng Wu1,2, Honglong Wu1,2

  • 1Department of Pharmacy, The First Affiliated Hospital of Bengbu Medical University, Bengbu, Anhui, China.

Frontiers in pharmacology
|July 24, 2025
PubMed
概括

瘤微环境中的与癌症相关的纤维细胞通过蛋白质分泌驱动非小细胞肺癌 (NSCLC) 中的Osimertinib耐药性. 用LL1准STAT3可以扭转这种抵抗,为NSCLC提供新的治疗策略.

关键词:
与癌症相关的纤维细胞.非小细胞肺癌的肺癌.奥西默蒂尼布的耐药性是异常的信号传感器和转录的激活器 3 3瘤微环境是一个微环境.

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