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Updated: Aug 2, 2026

Inducing Acute Lung Injury in Mice by Direct Intratracheal Lipopolysaccharide Instillation
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新型线粒诱导剂TJ0113在急性肺损伤期间缓解肺炎

Zhengyuan Liu1, Danruo Fang1, Kaijun Chen1

  • 1Key Laboratory of Respiratory Disease of Zhejiang Province, Department of Respiratory and Critical Care Medicine, Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.

Frontiers in pharmacology
|July 24, 2025
PubMed
概括

TJ0113,一种线粒诱导剂,在急性肺损伤 (ALI) 模型中有效降低了炎症和死亡率. 这种化合物向受损的线粒体,通过抑制关键炎症途径,为ALI提供了有前途的新疗法.

关键词:
在 NF-κBB 中.在NLRP3炎症酶组中,在TJ0113中,肺部急性肺损伤是什么诱导神经衰变的诱导剂

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