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Updated: Sep 14, 2025

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通过介质素1信号传递来调节成年海马神经发生

Maria I Smirnova1, Ning Quan1,2

  • 1Department of Biomedical Science, Charles E. Schmidt College of Medicine, Florida Atlantic University, 5353 Parkside Drive, Jupiter, FL, 33458, USA.

Neurobiology of sleep and circadian rhythms
|July 24, 2025
PubMed
概括

干白素-1 (IL-1) 信号传递以复杂的方式影响成人海马神经发生 (AHN). 了解这种关系是治疗神经和精神疾病的关键.

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Neurogenesis and Regeneration of Nervous Tissue01:15

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In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...
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