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甲状腺癌 - 一种新的术语,用于识别组织学上熟悉的实体
Revathi Krishna1, Aadithya B Urs1, Jeyaseelan Augustine1
1Department of Oral and Maxillofacial Pathology and Microbiology, Maulana Azad Institute of Dental Sciences, New Delhi, India.
Journal of oral and maxillofacial pathology : JOMFP
|July 24, 2025
概括
增殖性白血病 (PVL) 是一种具有高恶性潜力的口腔病变. 提出了一个新的类别,巴尔纳瘤 (BC),以改善PVL的诊断和治疗,将其与其他状病变区分开来.
科学领域:
- 口腔病理学 口腔病理学
- 在瘤学瘤学.
- 组织病理学 组织病理学
背景情况:
- 增殖性白血病 (PVL) 是一种具有高恶性转变潜力的口腔潜在恶性疾病 (OPMD).
- PVL病变呈现出各种临床和组织学表现,由于的表面扩散,往往导致诊断模两可.
- 目前的分类可能无法完全捕捉PVL独特的组织学谱.
研究的目的:
- 为了解决扩散性性白血病 (PVL) 的诊断挑战.
- 在PVL频谱中引入和定义一个新的组织病理学类别,巴纳瘤 (BC),在PVL频谱中.
- 为了区分BC与性增生症 (VH) 和性癌瘤 (VC).
主要方法:
- 审查和分析PVL病变的组织病理特征.
- 关于PVL的四个组织病理学类别的建议,包括新的实体巴纳瘤 (BC).
- 基于独特的形态特征的BC定义:重的,非侵入性的上皮细胞增殖与内生长,平面和完整的底层膜.
主要成果:
- 甲状腺癌 (BC) 被提议作为VH和VC之间的中间阶段.
- BC的特点是"坚持"的外观,类似于VC,但缺乏入侵.
- 在有限的随访中,BC没有报告结节转移或死亡.
结论:
- 拟议的BC类别可以完善PVL的诊断和治疗.
- 需要进一步的研究来验证BC的生物行为,并建立治疗方案.
- 在活检中识别BC对于未来OPMD的分类和管理策略至关重要.
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