孕产妇失脂症及其与早产和其他不良周产期结果的关联
Mona Mishra1, Neetu Singh1, Ayush Lohiya2
1Department of Obstetrics and Gynecology, Dr. Ram Manohar Lohia Institute of Medical Sciences, Lucknow, IND.
孕产妇失脂症与早产无关,但与低出生体重,新生儿重症监护室 (NICU) 停留时间较长以及新生儿需要光疗的风险增加有关.
科学领域:
- 产科和妇科 产科和妇科
- 新生儿科学 新生儿科学
- 怀孕期间的心血管健康
背景情况:
- 关于孕产妇脂质不良症和早产之间的关系,存在相互矛盾的证据.
- 有限的研究已经探索了孕产妇脂质不良症和其他不良周产期结果之间的联系,包括低出生体重 (LBW),新生儿重症监护室 (NICU) 入院,光疗,辅助呼吸和死胎.
研究的目的:
- 调查孕产妇脂质不良症与早产之间的关联.
- 确定孕产妇脱脂症对其他新生儿不良结果的影响:LBW,NICU停留,需要新生儿光疗,需要辅助呼吸和死胎.
主要方法:
- 一项前性观察性研究,涉及159名孕妇.
- 血清脂质概况的评估是在怀孕20至28周之间进行的.
- 在整个产前期,直到分娩为止,对患有脱脂症和患有脱脂症的妇女,都仔细记录了怀孕的结果.
主要成果:
- 在孕产妇的脂质不良症和早产之间没有发现显著的关联 (p = 0.69).
- 孕产妇脂质不良与新生儿低出生体重 (p = 0.06) 的增加率,NICU停留时间更长 (p = 0.005) 和新生儿光疗的更高需求 (p = 0.045) 显著相关.
- 观察到患有脱脂症的母亲产生的新生儿增加了对辅助通风的需求 (p = 0.064).
结论:
- 孕产妇的脂质不良症似乎不会增加早产的风险.
- 孕产妇的脂质不良症与新生儿不良结果有显著的关联,包括出生体重低,NICU入院增加,以及新生儿光疗的要求.
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