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Updated: Sep 14, 2025

Identification of Transcription Factor Regulators using Medium-Throughput Screening of Arrayed Libraries and a Dual-Luciferase-Based Reporter
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基化酶1A与YTHDF2进行物理相互作用,并加强非小细胞肺癌的进展

Chong Zhang1,2, Zuoyan Zhang3,4, Yueyi Wu2

  • 1Department of Oncology, Shangyu People's Hospital of Shaoxing, Shaoxing, China.

eLife
|July 24, 2025
PubMed
概括

二酶1A (PDE1A) 通过与YTHDF2相互作用来促进非小细胞肺癌 (NSCLC) 转移,从而破坏SOCS2的稳定并激活STAT3通路,从而提供新的治疗点.

关键词:
在NSCLCLC中,我们可以看到.这是一个PDE1A.在STAT3中,我们可以使用STAT3.这就是YTHDF2的原因.癌症生物学 癌症生物学细胞生物学 细胞生物学人类 人类 人类 人类 人类 人类 人类转移 转移 转移 转移

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