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从Candida auris殖民查到临床病例状况的进展,美国,2016-2023年

Anna D Baker, Jeremy A W Gold, Kaitlin Forsberg

Emerging infectious diseases

|July 24, 2025

概括

一项研究发现,6.9%的患有Candida auris的患者患上了临床感染,其中2.8%的血液感染. 这凸显了在被殖民个体中预防侵入性Candida auris感染的策略的需要.

科学领域:

传染性疾病传染性疾病
医学真菌学医学真菌学
公共卫生公共卫生

背景情况:

黄是一种新兴的多抗药性真菌病原体.
用Candida auris殖民是侵入性感染的危险因素.
对侵袭性Candida auris的有效预防策略至关重要.

研究的目的:

为了确定在殖民后临床Candida auris感染的发生率.
为了确定与侵入性Candida auris.相关的风险因素和结果.

主要方法:

对2016-2023年患者数据的回顾性分析.
包括阳性Candida auris殖民查的患者.
追踪随后的阳性临床标本,包括血液培养物.

主要成果:

在21195名患有Candida auris殖民的患者中,6.9%患有临床感染.
侵袭性血液感染发生在2.8%的殖民患者中.
显著比例的殖民患者进展到临床疾病.

结论:

殖民化与Candida auris构成后续侵袭性感染的重大风险.
患者去殖民化策略可能是减少侵袭性Candida auris的必要条件.
对殖民患者的预防措施的进一步研究是有必要的.

关键词:

黄虫 (Candida auris) 是一种有毒的植物.美国的美国.抗微生物耐药性抗微生物耐药性候选血病是什么意思候选血病是什么意思交叉感染交叉感染菌类药物耐药性菌类药物耐药性菌是一种真菌.感染控制的方法

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