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Updated: Sep 14, 2025

A Method for Mouse Pancreatic Islet Isolation and Intracellular cAMP Determination
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Published on: June 25, 2014

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一个PKA类型I调节子单元的相分离通过cAMP分离来调节β细胞功能

Ha Neul Lee1, Julia C Hardy1,2, Emily H Pool1,3

  • 1Department of Pharmacology, University of California, San Diego, La Jolla, California, United States of America.

PLoS biology
|July 24, 2025
PubMed
概括

液体-液体相分离 (LLPS) 的RIα子单元调节胰腺β细胞的功能,通过细分循环腺单酸盐 (cAMP). 这个过程控制和cAMP振荡,胰岛素分泌和细胞增殖.

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