海产多糖和它们的化学修饰衍生物作为生物医学应用先进生物功能材料的来源
Vera Sousa1, Luís P G Monteiro1, Djenisa H A Rocha1
1CICECO─Aveiro Institute of Materials, Department of Chemistry, University of Aveiro, Campus Universitário de Santiago, 3810-193 Aveiro, Portugal.
Biomacromolecules
|July 24, 2025
概括
海洋多糖为先进的应用提供可持续的,生物相容的材料. 本综述涵盖了它们的来源,性质,功能以及在生物材料中用于医药,食品和化品的用途.
科学领域:
- 生物材料科学 生物材料科学
- 海洋生物技术 海洋生物技术
- 聚合物化学 聚合物化学
背景情况:
- 海洋多糖是可持续的,可再生的宏分子,具有出色的生物相容性,生物降解性和非免疫性质.
- 它们与本地组织的结构相似性使得它们非常适合生物医学应用.
- 这些多糖是从各种海洋生物中获取的,存在于阴离子,阴离子和中性形式.
研究的目的:
- 提供海洋起源多糖的全面概述.
- 讨论它们的来源,特性和化学功能化策略.
- 探索将它们加工成用于各种应用的先进生物功能材料和设备.
主要方法:
- 关于海洋起源多糖的文献综述.
- 化学功能化技术的分析.
- 检查各种生物材料 (例如纳米粒子,水凝,薄膜) 的加工方法.
主要成果:
- 海洋多糖类可以被功能化并加工成各种形式,如纳米粒子,水凝和薄膜.
- 这些材料在抗微生物涂料,伤口包裹,药物输送和组织工程方面表现有前途.
- 例如,它们在食品包装,化品和体外疾病建模中的使用.
结论:
- 海洋起源的多糖是多功能生物材料,在再生医学,药物输送等领域具有重大潜力.
- 在临床翻译和商业化方面仍然存在挑战.
- 未来的研究应该集中在克服这些障碍,以充分利用他们的能力.
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