在患有注意力缺陷多动性障碍的青少年中,低度炎症,认知功能障碍,冲动性和食欲激素失调
Li-Chi Chen1, Ya-Mei Bai2, Shih-Jen Tsai2
1Department of Psychiatry, Taipei Veterans General Hospital, Taipei, Taiwan; Department of Psychiatry, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan; Department of Psychiatry, Cheng Hsin General Hospital, Taipei, Taiwan.
患有注意力缺陷多动症 (ADHD) 和低级炎症 (LGI) 的青少年表现出增加的冲动性,改变的食欲激素和较差的认知功能. 这表明青春期的ADHD是一种免疫代谢亚型.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 免疫学 免疫学 免疫学
背景情况:
- 注意缺陷多动症 (ADHD) 具有已识别的炎症生物型.
- 青少年中低度炎症 (LGI),多动症症状,食欲激素和认知之间的联系还不清楚.
研究的目的:
- 研究LGI,临床症状,食欲激素调节和ADHD青少年的认知功能之间的关系.
- 为了识别潜在的ADHD免疫代谢亚型.
主要方法:
- 评估了88名患有多动症的青少年和65名健康对照人群.
- 根据C反应蛋白水平或体重指数来定义LGI.
- 参与者完成了冲动度量表 (BIS),认知任务 (去/不去,WCST) 和行为症状问卷 (SNAP-IV).
主要成果:
- 18.2%的患有多动症的青少年有LGI.
- 有LGI的ADHD显示出更高的冲动性,注意力低下和自我控制能力差 (BIS得分).
- 这一组表现出胰岛素和瘦素水平升高,以及认知任务的表现受损.
结论:
- 研究结果表明,ADHD是一种免疫代谢亚型.
- 患有ADHD和LGI的青少年经历了更严重的冲动性和认知缺陷.
- 胃口激素水平受到干扰与这种ADHD亚型有关.
更多相关视频
13:09Using Brain Activation nir-HEG/Q-EEG and Execution Measures CPTs in a ADHD Assessment Protocol
Published on: April 1, 2018
10:02Event Related Potentials ERPs and other EEG Based Methods for Extracting Biomarkers of Brain Dysfunction: Examples from Pediatric Attention Deficit/Hyperactivity Disorder ADHD
Published on: March 12, 2020
相关概念视频
Attention-Deficit/Hyperactivity Disorder
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
Human Genetics
The complex relationship between genetics and psychology is observable through common biological components such...
Stress and Mental Health
Individuals with depression often experience challenges in both their personal and professional...
Cognitive Development During Adolescence
Depression: Overview
Major Hormones and Their Functions
Oxytocin, produced in the hypothalamus and released by the pituitary gland, plays a role in social bonding, childbirth, and...
