在PET/CT检查中,Safire CT代重建协议可降低患者有效剂量
Alice Ferretti1, Sotirios Chondrogiannis2, Jlenia Peretto2
1Medical Physics Unit, Santa Maria della Misericordia Hospital of Rovigo, ULSS5 Polesana, Rovigo, Italy.
概括
在3级的Siemens SAFIRE代重建可以在18F-FDG PET/CT扫描中将CT剂量降低高达40%,而不会影响图像质量或SUV精度. 这种方法显著降低了患者的辐射暴露,从10.1mSv降至8.3mSv.
科学领域:
- 医疗成像医学成像
- 辐射物理学 辐射物理学
- 核医学是一种核医学.
背景情况:
- 标准过后投影 (FBP) 在PET/CT中CT重建限制剂量降低.
- 代重建技术可以降低剂量,同时保持图像质量.
研究的目的:
- 实施和评估CT代重建 (SAFIRE) 以减少18F-FDG PET/CT的剂量.
- 评估SAFIRE对图像质量和标准化吸收值 (SUV) 准确性的影响.
主要方法:
- 使用Catphan 600和Alderson-Rando幻影来测试SAFIRE在降低mA设置的情况下.
- 使用NEMA 2012年智商幻影评估PET的定量准确性.
- 对25名患者进行临床评估,将SAFIRE与FBP进行比较.
主要成果:
- SAFIRE 3级降低CT剂量~40% (幻影) 和30% (人形幻影) 没有降低噪音或CNR.
- 在剂量优化的代重建中,PET SUV值显示出最小的偏差 (<0.6%).
- 临床评估证实,与FBP相比,SAFIRE降低剂量的图像质量不劣.
结论:
- 在3级的SAFIRE代重建有效地将全身PET/CT中平均有效剂量降低了1.8mSv.
- 这种剂量降低可以实现,而不会损害图像质量或SUV精度.
- 在PET/CT检查中,SAFIRE提供了一种可行的策略来降低患者的辐射暴露.
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