肌肉力量失衡预测脚复发风险:一种肌肉骨建模方法
Christian Greve1, Bryce A Killen2, G J F Joyce Bos3
1Department of Rehabilitation Medicine, University of Groningen, University Medical Center Groningen, the Netherlands; Department of Human Movement Sciences, University of Groningen, University Medical Center Groningen, the Netherlands.
Computer methods and programs in biomedicine
|July 24, 2025
概括
经常出现的脚与肌肉和关节不平衡有关. 先进的肌肉骨建模揭示了改变肌肉强度和关节性如何导致复发,为个性化治疗铺平了道路.
科学领域:
- 生物力学 生物力学
- 整形外科的研究研究.
- 计算建模 计算建模
背景情况:
- 在Ponseti方法治疗后的20-40%病例中,异形脚会复发.
- 复发通常归因于肌肉和带力失衡,影响步行期间的脚和脚的关节对齐.
研究的目的:
- 调查导致异常类脚复发的生物力学因素.
- 利用先进的肌肉骨建模来分析这些因素.
主要方法:
- 从一个典型发育的儿童收集实验数据 (3D细分位置,肌肉活动,地面反应力).
- 在下肢肌肉骨模型上优化肌肉和肌参数.
- 系统地操纵了evertor肌肉强度和invertor肌肉度,并改变了关节几何形状以模拟脚复发.
- 通过反向动态分析评估了脚和脚关节的动量平衡.
主要成果:
- 肌肉骨模型对肌肉强度,关节硬度和关节几何学的小变化表现出敏感性.
- 降低了恒流体肌肉力量 (到正常的30%),足以在没有反转力的情况下保持典型的动力学.
- 逆变器肌肉硬度增加和逆变关节硬度 (>30%) 显著提高了逆变器强度需求,并导致动力学异常.
- 关节对齐的变化模仿脚的复发影响了肌肉时刻和手臂平衡.
结论:
- 先进的肌肉骨建模可以确定脚复发的机械因素.
- 这些发现支持使用患者特定数据来验证临床预测.
- 这种方法可以实现个性化治疗策略,以改善复发性脚病的治疗结果.
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