儿童重症监护病房中获得的弱点的风险因素和6个月后的结果
Min Ding1, Chunfeng Yang1, Yanling Qin2
1Department of Pediatric Intensive Care Unit, Children's Medical Center, The First Hospital of Jilin University, Changchun, China.
概括
儿科重症监护室获得的虚弱 (PICU-AW) 影响25.6%的儿童,与最初的疾病严重程度和更长的PICU停留有关. PICU-AW独立地影响出院后的生活质量.
科学领域:
- 儿科重症监护医学 儿科重症监护医学
- 神经肌肉疾病 神经肌肉疾病
- 生活质量研究 研究 生命质量研究
背景情况:
- 儿科重症监护室获得的虚弱 (PICU-AW) 尚未得到充分研究,但与预后不佳有关.
- 了解PICU-AW对于改善患者的治疗结果和资源配置至关重要.
研究的目的:
- 确定儿童发展PICU-AW的危险因素.
- 为了评估在出院后PICU-AW儿童的6个月后的结果.
主要方法:
- 一项前性观察研究包括172名儿童 (年龄在7-18岁) 从2021年5月到2022年12月.
- 用单变量和多变量逻辑回归分析了风险因素.
- 包括肌肉强度,功能状态和HRQOL在内的结果在出院后的1,3,6个月被评估.
主要成果:
- 44名儿童 (25.6%) 被诊断出患有PICU-AW.
- 系统性炎症反应综合征,更高的儿科物流器官功能障碍2分数和更长的PICU停留时间是PICU-AW的重要风险因素.
- PICU-AW是退院后1个月和3个月降低HRQOL的独立风险因素,但在6个月内没有功能状态.
结论:
- 系统性炎症反应综合征,器官功能障碍和长时间的PICU停留是PICU-AW的关键风险因素.
- 在短期内,PICU-AW在出院后显著降低了与健康有关的生活质量.
- 具有正常基线功能的儿童表现出更好的功能状态恢复.
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