在Staphylococcus aureus bacteremia中探索时间与阳性度和阳性培养瓶数之间的相关性:对转移性病变发展的影响
Kazuhiro Ishikawa1, Satoru Sekiya1, Nobuyoshi Mori1
1Department of Infectious Diseases, St Luke's International Hospital, Tokyo, Japan.
概括
阳性时间 (TTP) 和阳性血液培养瓶数并不能预测黄金杆菌菌菌病的严重程度或死亡率. 较短的TTP可能表明血管内或骨感染,需要进一步调查.
科学领域:
- 传染性疾病 传染性疾病
- 临床微生物学 临床微生物学
- 细菌学 细菌学是一门学科.
背景情况:
- 血液培养时间到阳性 (TTP),阳性瓶数和Staphylococcus aureus (S. aureus) 细菌病的结果之间的关系尚未明确定义.
- 这项研究调查了TTP和阳性瓶数对S. aureus细菌病重度,死亡率和转移性病变形成的影响.
研究的目的:
- 确定TTP和阳性血液培养瓶的数量是否可以预测S. aureus bacteremia的严重程度和死亡率.
- 探索TTP与S. aureus bacteremia转移性病变的发展之间的关联.
主要方法:
- 对317名被诊断患有S. aureus bacteremia的患者进行了回顾性分析.
- 时间到阳性 (TTP) 和阳性血培瓶数量的评估.
- 对TTP,阳性瓶数,死亡率,严重程度和转移性病变之间的相关性分析.
主要成果:
- 没有发现TTP或阳性瓶数与S. aureus bacteremia的死亡率或严重程度之间有显著的关联.
- 与一般细菌病 (23.45小时) 相比,在血管内感染 (16.81小时) 和骨/关节感染 (17.88小时) 的患者中观察到较短的TTP.
- 在TTP和转移性病变数量 (r=0.203) 之间以及在TTP和阳性瓶子数量 (r=0.544) 之间观察到较弱的相关性.
结论:
- 阳性时间 (TTP) 和阳性瓶数不是S. aureus bacteremia的严重程度或死亡率的可靠预测指标.
- 较短的TTP (大约或低于20小时) 可能表明血管内或骨/关节感染,需要进一步的临床评估.
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