益生菌:慢性呼吸道疾病的辅助治疗策略
Bharti Verma1, Nitish Kumar1, Sumel Ashique2
1SRM Modinagar College of Pharmacy, Faculty of Medicine and Health Sciences, SRM Institute of Science and Technology, Delhi-NCR Campus, Delhi-Meerut Road, Modinagar, Ghaziabad, UP, India.
Respiratory medicine
|July 24, 2025
概括
用益生菌调节肠道微生物组可能有助于减少呼吸道感染. 虽然临床症状没有改善,但通过鼻子输送益生菌对慢性炎症性肺部疾病有希望.
科学领域:
- 微生物学 微生物学
- 免疫学 免疫学 免疫学
- 肺部病理学 肺部病理学
背景情况:
- 慢性呼吸道疾病是导致死亡的主要原因,其特点是空气流量减少和炎症.
- 肠肺轴突出了肠道微生物群和肺部健康之间的联系.
- 肠道疾病与增加肺部感染风险有关.
研究的目的:
- 探索肠道微生物组调节在呼吸系统健康中的作用.
- 评估益生菌,益生菌和共生菌在治疗呼吸系统疾病中的有效性.
- 调查内益生菌在炎症性肺部疾病中的潜在作用.
主要方法:
- 对呼吸道疾病的肠道微生物群干预研究的综述.
- 分析益生菌对免疫标记物如细胞因子和IgE的影响.
- 口服与鼻内益生菌药物给药途径的比较.
主要成果:
- 益生菌可以改变免疫标记物,并减少过敏症和喘中的eosinophilia.
- 在接受益生菌治疗的COPD患者中没有观察到显著的临床症状改善.
- 与口服相比,鼻内益生菌的输送可能会提高疗效.
结论:
- 肠道微生物组调节显示出管理呼吸道感染和炎症的潜力.
- 通过鼻子输送益生菌是一种有前途的治疗策略,用于慢性炎症性肺部疾病.
- 需要进一步的研究来优化各种影响因素的干预措施.
相关概念视频
Drugs Used in Lower Respiratory Disorders: Overview
589
Lower respiratory tract disorders present challenges that often require skilled and nuanced approaches for effective management. Common ailments, such as asthma and chronic obstructive pulmonary disease (COPD), have prompted the development of intricate treatment strategies involving bronchodilators and anti-inflammatory drugs, each tailored to ease breathing and revitalize the lungs.
Bronchodilators, the first step of respiration enhancement, come in various forms, each with its own mechanism...
Bronchodilators, the first step of respiration enhancement, come in various forms, each with its own mechanism...
589
Chronic Obstructive Pulmonary Disease-V: Management
2.7K
Managing Chronic Obstructive Pulmonary Disease (COPD) involves a multifaceted approach to reduce symptoms, prevent exacerbations, improve overall health status, and slow disease progression. Key strategies include lifestyle modifications, pharmacotherapy, supportive therapies, and, in some cases, surgery. Here is an overview of the primary COPD management strategies:
Smoking Cessation
Smoking Cessation
2.7K
Drugs Used in Upper Respiratory Disorders: Overview
367
Upper respiratory tract disorders, including viral infections and allergic rhinitis, cause significant discomfort and disrupt daily life. Managing these conditions involves a variety of drugs, such as antihistamines, intranasal steroids, decongestants, antitussives, expectorants, and mucolytics. Specific examples of drugs in each category are provided.
Antihistamines (e.g., Benadryl) block histamines from binding. Histamines are chemicals released during an allergic reaction in the body. As a...
Antihistamines (e.g., Benadryl) block histamines from binding. Histamines are chemicals released during an allergic reaction in the body. As a...
367
Microorganisms in Medicine and Therapeutics
345
Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
345
Acute Respiratory Failure-V
209
The treatment for acute respiratory failure varies based on factors like the underlying cause, overall health, and severity. A collaborative healthcare team is essential for early detection, often through arterial blood gas analysis. Identifying the cause is the primary goal, with treatment strategies adjusted for ventilation/perfusion (V/Q) mismatch, shunting, or diffusion impairment.
Ensure that patients are monitored continuously for their response to therapy, including changes in...
Ensure that patients are monitored continuously for their response to therapy, including changes in...
209
Asthma: Pathogenesis and Management
597
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
597


